A research paper, entitled “Advances in cancer DNA methylation analysis with methPLIER: use of non-negative matrix factorization and knowledge-based constraints to enhance biological interpretability” was published in the Experimental & Molecular Medicine.
The research team includes Ken Takasawa (Research Scientist), Ryuji Hamamoto (Team Leader) of the Cancer Translational Research Team, at RIKEN AIP.
Authors:
Ken Takasawa, Ken Asada, Syuzo Kaneko, Kouya Shiraishi, Hidenori Machino, Satoshi Takahashi, Norio Shinkai, Nobuji Kouno, Kazuma Kobayashi, Masaaki Komatsu, Takaaki Mizuno, Yu Okubo, Masami Mukai, Tatsuya Yoshida, Yukihiro Yoshida, Hidehito Horinouchi, Shun-Ichi Watanabe, Yuichiro Ohe, Yasushi Yatabe, Takashi Kohno, Ryuji Hamamoto (*Corresponding Author)
For more information, please see the following URL.
https://www.ncc.go.jp/jp/information/researchtopics/2024/0305/index.html
