ジャーナル論文 / Journal
  1. Suzuki, H., Egawa, N., Imamura, K., Kondo , T., Enami, T., Tsukita, K., Suga, M., Yada, Y., Shibukawa, R., Takahashi, R., and Inoue, H., "Mutant α-synuclein causes death of human cortical neurons via ERK1/2 and JNK activation", Mol. Brain, (2024).
  2. Suong, D. N., Imamura, K., Kato, Y., and Inoue, H., "Design of neural organoids engineered by mechanical forces", IBRO Neuroscience Reports, (2024).
  3. Otsuka, Y., Imamura, K., Oishi, A., Asakawa, K., Kondo, T., Teranaka, K., Suga, M., Inoue, I., Sagara, Y., Tsukita, K., Teranaka, K., Nishimura, Y., Watanabe, A., Umeyama, K., Okushima, N., Mitani, K., Nagashima, H., Kawakami, K., Muguruma, K., Tsujikawa, A., and Inoue, H., "Phototoxicity avoidance is a potential therapeutic approach for retinal dystrophy caused by EYS dysfunction", JCI Insight. 2024;9(8):e174179. 9(8), (2024).
  4. Niwa, R., Matsumoto, T., Liu, A. Y., Kawato, M., Kondo, T., Tsukita, K., Inoue, H., Maurissen, T. L., and Woltjen, K., "Enrichment of allelic editing outcomes by Prime Editing in iPS cells", bioRxiv, 2024.03.19.585665, (2024).
  5. Munezane, H., Imamura, K., Fujimoto, N., Hotta, A., Yukitake, H., and Inoue, H., "Elimination of the extra chromosome of Dup15q syndrome iPSCs for cellular and molecular investigation", Eur. J. Cell Biol. 103(3), 151446, (2024).
  6. Yoshikawa, T., Oguchi, A., Toriu, N., Sato, Y., Kobayashi, T., Ogawa, O., Haga, H., Sakurai, S., Yamamoto, T., Murakawa, Y., and Yanagita, M., "Tertiary Lymphoid Tissues Are Microenvironments with Intensive Interactions between Immune Cells and Proinflammatory Parenchymal Cells in Aged Kidneys", J. Am. Soc. Nephrol. 34(10), 1687–1708, (2023).
  7. Mulia, I. E., Ueda, N., Miyoshi, T., Iwamoto, T., and Heidarzadeh, M., "A novel deep learning approach for typhoon-induced storm surge modeling through efficient emulation of wind and pressure fields", Sci. Rep. 13(1), 7918, (2023).
  8. Kondo, T., Inoue, I., Umeyama, K., Watanabe, M., Matsunari, H., Uchikura, A., Nakano, K., Tsukita, K., Imamura, K., Nagashima, H., and Inoue, H., "A Transgenic Pig Model With Human Mutant SOD1 Exhibits the Early Pathology of Amyotrophic Lateral Sclerosis", Lab. Invest. 103(2), 100013, (2023).
  9. Hirayama, T., Shibukawa, M., Morioka, H., Hozumi, M., Tsuda, H., Atsuta, N., Izumi, Y., Nakayama, Y., Shimizu, T., Inoue, H., Urushitani, M., Yamanaka, K., Aoki, M., Ebihara, S., Takeda, A., and Kano, O., "The necessity to improve disaster preparedness among patients with amyotrophic lateral sclerosis and their families", Journal of Clinical Neuroscience 116, 87–92, (2023).
  10. Yuki, S., Akiko, O., Fukushima, Y., Masuda, K., Toriu, N., Taniguchi, K., Yoshikawa, T., Cui, X., Kondo, M., Hosoi, T., Komidori, S., Shimizu, Y., Fujita, H., Jiang, L., Kong, Y., Yamanashi, T., Seita, J., Yamamoto, T., Toyokuni, S., Hamazaki, Y., Hattori, M., Yoshikai, Y., Boor, P., Floege, J., Kawamoto, H., Murakawa, Y., Minato, N., and Yanagita, M., "CD153/CD30 signaling promotes age-dependent tertiary lymphoid tissue expansion and kidney injury", J. Clin. Invest. 132(2), e146071, (2022).
  11. Sawamura, M., Imamura, K., Hikawa, R., Enami, T., Nagahashi, A., Yamakado, H., Ichijo, H., Fujisawa, T., Yamashita, H., Minamiyama, S., Kaido, M., Wada, H., Urushitani, M., Inoue, H., Egawa, N., and Takahashi, R., "Cellular analysis of SOD1 protein-aggregation propensity and toxicity: a case of ALS with slow progression harboring homozygous SOD1-D92G mutation", Sci. Rep. 12(1), (2022).
  12. Ozaki, H., Suga, H., Sakakibara, M., Soen, M., Miyake, N., Miwata, T., Taga, S., Nagai, T., Kano, M., Mitsumoto, K., Miyata, T., Kobayashi, T., Sugiyama, M., Onoue, T., Takagi, H., Hagiwara, D., Iwama, S., Banno, R., Iguchi, G., Takahashi, Y., Muguruma, K., Inoue, H., and Arima, H., "Differentiation of human induced pluripotent stem cells into hypothalamic vasopressin neurons with minimal exogenous signals and partial conversion to the naive state", Sci. Rep. 12(1), (2022).
  13. Otsuka, Y., Imamura, K., Oishi, A., Kondo, T., Suga, M., Yada, Y., Shibukawa, R., Okanishi, Y., Sagara, Y., Tsukita, K., Tsujikawa, A., and Inoue, H., "One-step induction of photoreceptor-like cells from human iPSCs by delivering transcription factors", iScience 20(4), (2022).
  14. Okuda, S., Nakayama, T., Uemura, N., Hikawa, R., Ikuno, M., Yamakado, H., Inoue, H., Tachibana, N., Hayashi, y., Takahashi, R., and Egawa, N., "Striatal-Inoculation of α-Synuclein Preformed Fibrils Aggravated the Phenotypes of REM Sleep without Atonia in A53T BAC-SNCA Transgenic Mice", Int. J. Mol. Sci. 23(21), (2022).
  15. Nagano, M., Hu, B., Yokobayashi, S., Yamamura, A., Umemura, F., Coradin, M., Ohta, H., Yabuta, Y., Ishikura, Y., Okamoto, I., Ikeda, H., Kawahira, N., Nosaka, Y., Shimizu, S., Kojima, Y., Mizuta, K., Kasahara, T., Imoto, Y., Meehan, K., Stocsits, R., Wutz, G., Hiraoka, Y., Murakawa, Y., Yamamoto, T., Tachibana, K., Peters, J., Mirny, L. A., Garcia, B. A., Majewski, J., and Saitou, M., "Nucleome programming is required for the foundation of totipotency in mammalian germline development", The EMBO Journal 41(13), e110600, (2022).
  16. Kondo, T., Yada, Y., Ikeuchi, T., and Inoue, H., "CDiP technology for reverse engineering of sporadic Alzheimer’s disease", J. Hum. Genet., (2022).
  17. Kondo, T., Hara, N., Koyama, S., Yada, Y., Tsukita, K., Nagahashi, A., Ikeuchi, T., Ishii, K., Asada, T., Arai, T., Yamada, R., Alzheimer’s Disease Neuroimaging Initiative (ADNI), Japanese Alzheimer’s Disease Neuroimaging Initiative (J-ADNI), and Inoue, H., "Dissection of the polygenic architecture of neuronal Aβ production using a large sample of individual iPSC lines derived from Alzheimer’s disease patients", Nature Aging 2, 125–139, (2022).
  18. Egawa, N., Izumi, Y., Suzuki, H., Tsuge, I., Fujita, K., Shimano, H., Izumikawa, K., Takahashi, N., Tsukita, K., Enami, T., Nakamura, M., Watanabe, A., Naitoh, M., Suzuki, S., Seki, T., Kobayashi, K., Toda, T., Kaji, R., Takahashi, R., and Inoue, H., "TDP-43 regulates cholesterol biosynthesis by inhibiting sterol regulatory element-binding protein 2", Sci. Rep. 12(1), (2022).
  19. Egawa, N., Hamanaka, G., Chung, K. K., Ishikawa, H., Shindo, S., Maki, T., Takahashi, R., Inoue, H., Lo, E. H., and Arai, K., "High Mobility Group A1 Regulates Transcription Levels of Oligodendrocyte Marker Genes in Cultured Oligodendrocyte Precursor Cells", Int. J. Mol. Sci. 23(4), (2022).
  20. 松島早希, 今村恵子, 井上治久, "人工知能を用いた筋萎縮性側索硬化症の研究", Medical Sciencen Digest 48(1), (2021).
  21. 井上治久, 柴田圭輔, 今村恵子, 行武洋, "iPS細胞を用いた自閉症と認知症の研究", 月刊細胞 53(11), (2021).
  22. 井上治久, 奥宮太郎, 坂野晴彦, "iPS細胞を用いた認知症疾患修飾薬の開発", 老年精神医学雑誌 32(11), (2021).
  23. 井上治久, 塩田隼士, "iPS細胞を用いたAI創薬プラットフォーム", 月間ファームステージ 21(4), 40–44, (2021).
  24. 井上治久, 坂野晴彦, 奥宮太郎, "iPS細胞を用いた創薬", クリーンテクノロジー 2021年10月号 31(10), (2021).
  25. Yada, Y., Suga, M., Shibukawa, R., Sagara, Y., Okanishi, Y., Enami, T., Tsukita, K., Kondo, T., Imamura, K., Sugihara, G., Murai, T., and Inoue, H., "Establishment of induced pluripotent stem cells from schizophrenia discordant fraternal twins", stem cell res., (2021).
  26. Yada, Y., Kondo, T., Suga, M., Tsukita, K., Enami, T., Shibukawa, R., Sagara, Y., Okanishi, Y., Imamura, K., Kihara, T., and Inoue, H., "Human induced pluripotent stem cells generated from a patient with idiopathic basal ganglia calcification", stem cell res. 53, (2021).
  27. Tan, G. W., Kondo, T., Imamura, K., Suga, M., Enami, T., Nagahashi, A., Tsukita, K., Inoue, I., Kawaguchi, J., Shu, T., and Inoue, H., "Simple derivation of skeletal muscle from human pluripotent stem cells using temperature-sensitive Sendai virus vector", J. Cell. Mol. Med., (2021).
  28. Taguchi, J., Shibata, H., Kabata, M., Kato, M., Fukuda, K., Tanaka, A., Ohta, S., Ukai, T., Mitsunaga, K., Yamada, Y., Nagaoka, S., Yamazawa, S., Ohnishi, K., Woltjen, K., Ushiku, T., Ozawa, M., Saitou, M., Shinkai, Y., Yamamoto, T., and Yamada, Y., "DMRT1-mediated reprogramming drives development of cancer resembling human germ cell tumors with features of totipotency", Nat. Commun. 12(1), (2021).
  29. Imamura, K., Sakurai, Y., Enami, T., Shibukawa, R., Nishi, Y., Ohta, A., Shu, T., Kawaguchi, J., Okada, S., Hoenen, T., Yasuda, J., and Inoue, H., "iPSC screening for drug repurposing identifies anti-RNA virus agents modulating host cell susceptibility", FEBS Open Bio, (2021).
  30. Imamura, K., Kawaguchi, J., Tsugumine, S., and Inoue, H., "Generation of Motor Neurons from Human ESCs/iPSCs Using Sendai Virus Vectors", Neural Reprogramming, Springer, 127–132, (2021).
  31. Dang, S. N., Imamura, K., Inoue, I., Kabai, R., Sakamoto, S., Okumura, T., Kato, Y., Kondo, T., Yada, Y., Klein, W. L., Watanabe, A., and Inoue, H., "Induction of inverted morphology in brain organoids by vertical-mixing bioreactors", Commun. Biol., (2021).
国際会議 / Proceedings
  1. Murakami, S., Fujita, K., Ichimura, T., Hori, T., Hori, M., Lalith, M., and Ueda, N., "Development of 3D Viscoelastic Crustal Deformation Analysis Solver with Data-Driven Method on GPU", Lecture Notes in Computer Science, (2023).
レビュー / Review
  1. 仲井理沙子, 近藤孝之, 井上治久, "iPS 細胞由来神経系細胞を用いたアルツハイマー病の疾患モデリング", Medical Science Digest, (2024).
  2. 鈴木英文, 今村恵子, 井上治久, "iPS細胞技術を用いた神経変性疾患研究", 実験医学 41(12), (2023).
  3. 河野岳生, 近藤孝之, 井上治久, "iPS細胞とAIによる神経変性疾患早期診断の展望", Neuro Logica 7, (2023).
  4. 菅三佳, 井上治久, "iPS細胞研究の新知見からの発展：脳オルガノイドによるてんかんの病態研究", 日本臨牀 80(12), (2022).
  5. 仲井理沙子, 近藤孝之, 今村恵子, 井上治久, "iPS細胞技術を用いた神経変性疾患の解析", 生命の科学 74(5), (2022).
  6. 井上治久, 近藤孝之, "iPS細胞を用いたアルツハイマー病研究", アルツハイマー病治療の新たなストラテジー, (2022).